GSK Production System (GPS) Practitioner/ / Lean Six Sigma Practitioner

GSK
King of Prussia, PA
Site Name: USA - Pennsylvania - King of Prussia
Posted Date: Aug 29 2025

We make and supply medicines and vaccines all around the globe and our teams own every production stage, from creating quality products at our manufacturing sites to designing effective supply forecasting and regulatory inspections; all powered by digital, data and analytics. We operate at impressive scale, producing over 1.7 billion packs of medicine and 767 vaccine doses in 2021.

We continue to modernize, so we can launch even more new products at speed whilst turbo-charging delivery across our entire portfolio through our relentless focus on quality, safety, and service. The way we work will change. For some, the shift in technology and products will be revolutionary. Our R&D pipeline demands a new kind of supply chain, and we need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of automation and robotics so we can work smarter together.

The Site GPS Practitioner role is responsible for deploying, embedding, and sustaining the GSK Production System (GPS) within the Site to deliver the Business Strategy and to improve Business Performance across Safety, Quality, Service, Cost, & People.

As an expert in GPS, they work directly with the business, including those in direct zone roles (manufacturing, labs, warehouse), those in indirect zones (office-based) roles, and leaders up to and including the Site Leadership Team (SLT). They are responsible for developing the capability of site personnel to work with the GPS standards and tools, to continuously improve, and to encourage and engage all to proactively make improvements. They will contribute to the delivery of significant site objective improvement initiatives across all business and manufacturing processes. This lean leader role will be a Business Partner to Value Stream Leads to improve business through GPS maturity and performance. This role will add value to patients and business by driving a zero-waste supply chain and making efficiencies, including the use of digital, data and analytics tools in conjunction with Lean Leadership and behaviors.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Role model GPS and lean leadership behaviors and be a subject matter expert in GPS and Six Sigma.
  • Lead Accelerator improvements in Operations with their value stream lead partners.
  • Partner with GPS Lead to build and maintain GPS expertise within the Functional Group (Transformation Team)
  • Deliver improvement results aligned to site performance objectives and current GPS framework/standards as agreed with Site GPS Lead, and central GPS team.
  • Support the Site GPS Lead to periodically assess GPS maturity across site, including support of external assessments.
  • Support Leaders with site strategy definition, deployment, and translations for our site to ensure focused and aligned priorities.
  • Lead clarification of problems and align people to solve them at all levels of the organization. Assist in the execution of business-critical improvements across the site (i.e. lead-time, productivity).
  • Provide training and expert advice on GPS standards based on in-depth understanding and experience.
  • Provide high-quality coaching to staff at all levels of the business to develop and sustain GPS mindsets and behaviors.
  • Understand the role and potential use of digital, data, and analytics and/or automation tools where appropriate. Work collaboratively with the SMART manufacturing team, as required.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • Bachelor’s Degree
  • Green Belt Certification in Lean Six Sigma
  • 1+ year of experience with Manufacturing, Engineering, Operations, EHS, SCO, Quality, Laboratory, and/or Strategy
  • 2+ years of operational excellence or lean experience

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Experience in systems management or administrator, demonstrated leadership in change and transformation
  • Post-graduate qualification in Engineering, Lean or Six Sigma
  • Experience with Biopharmaceuticals or other cGMP environment
  • Black Belt Lean/Six Sigma Certification; or industry equivalent
  • Experience in coaching or directly leading a team
  • Change Management experience including leadership of complex projects/programs and teams.
  • Proven ability to build relationships and influence at all levels of the organization.
  • Highly effective communication skills with proven ability to build relationships and influence at all levels of the organization.
  • Diagnosis of complex performance issues and improvement initiatives in the context of site goals.
  • Strong coaching and training skills.
  • Program planning and execution management.


#LI-GSK

Please visit GSK US Benefits Summary t o learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at

Posted 2025-08-29

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