Senior Manager, HTA, Value and Evidence (HV&E), Solid Tumors

Pfizer
Harrisburg, PA

ROLE SUMMARY

The Senior Manager, HV&E, Solid Tumors will support the strategic goals of the Oncology Division by driving optimal patient access for our medicines.

This role directly impacts the ability to achieve business objectives on a global basis by providing strategic guidance and robust evidence development to achieve optimal patient access. This role will focus on demonstrating the value of an innovative therapy being studied for the treatment of multiple solid tumors. The role will be responsible for developing and executing against the global evidence generation strategy, including direct oversight of evidence generation activities and dissemination of technical deliverables.

This role will be part of Pfizer's dynamic Global Access & Value (GAV) team and will have the important role of managing health economics and outcomes research (HEOR) to generate data to support patient access. This position will be working closely with the GAV, cross-functional, and country teams to foster a culture that promotes innovation and thrives on doing better for Pfizer's patients and healthcare.

ROLE RESPONSIBILITIES

  • Provide strategic input into clinical trial designs (eg, patient populations, comparators, endpoints) and analysis plans to enable successful negotiations, reimbursement, and appropriate patient access with global payer and regulatory decision makers.

  • Develop and execute the clinical outcomes assessment strategy and incorporate humanistic and economic endpoints into clinical trials across all phases of product development to build comprehensive trial-based evidence aligned with overall asset strategy and to ensure global reimbursement and access requirements.

  • Help to develop and execute the Value & Evidence Strategy (VES) to support the value of this innovative therapy in close partnership with the cross-functional matrix team and local country/regional teams.

  • Lead the design and execution of global HEOR studies (eg, network meta-analyses, non-interventional studies, economic models) from concept through publication.

  • Lead the timely development of reimbursement deliverables to successfully support reimbursement and access requirements in conjunction with the regions/countries.

  • Partner with internal stakeholders to ensure appropriate customer-facing dissemination of HEOR materials.

  • Develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.

  • Remain fully compliant with all Pfizer SOPs (standard operating procedures).

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  • Master's degree (MSc, MPH) in HEOR-relevant field such as health services research, health economics, epidemiology, pharmacy administration/pharmaceutical policy, or other research-focused public health field. Doctoral degree (PhD, DrPH, ScD, PharmD) in relevant fields preferred.

  • Minimum 1 year of experience with PhD/DrPH/ScD/PharmD; minimum of 5 years of experience with MS/MPH; minimum of 6 years of experience with a Bachelor's degree, in early development, clinical trials, patient reported outcomes, and real world study design and implementation is desirable

  • Demonstrated understanding of fundamental health services research methods (e.g., health economics, patient-reported outcomes, research study design, database analyses, epidemiology, and statistics) and external environmental trends influencing health care/pharmaceuticals in key markets worldwide

  • Demonstrated ability to manage multiple projects involving complex processes, significant budget, competing deadlines and rapidly shifting priorities

  • Excellent interpersonal skills required; ability to understand and respond to multiple internal and external customers and influence in a matrix environment

  • Excellent oral and written English communication skills required

  • Strong project management abilities (e.g., contracting, budgeting, vendor management) essential

  • Skilled in functioning within a matrix organization where managing through influence is required

PREFERRED QUALIFICATIONS

  • Knowledge and experience in the oncology therapeutic area is highly preferred along with experience with solid tumor products

  • Experience with various real-world data types and sources and a publication track record of working with these sources is preferred

  • Experience interacting with country teams and knowledge of global HTA requirements and HTA organizations (e.g., NICE, GBA, HAS, CDA, PBAC, ICER) and other access-related stakeholders (e.g., US pathways).

Other Job Details:

  • Last Date to Apply for Job: April 22nd, 2026.

  • Locations: United States - any Pfizer site; Europe - Any Pfizer site

  • Ability to travel domestically and internationally based on business needs

  • Ability to work in all US time zones

  • NOT eligible for Relocation Package

  • This position is hybrid and requires working onsite 2 to 3 days per week

#LI-PFE

The annual base salary for this position ranges from $139,100.00 to $231,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

Market Access

Posted 2026-05-03

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