Hepatology Scientist

Insight Global
Elwyn, PA

Job Description

One of our large pharmaceutical clients is actively hiring a Hepatology Scientist to join their R&D Team. Primary goal of this project is to develop robust and reproducible human primary cell-derived complex in vitro model for steatotic liver disease demonstrating the fibrotic and inflammatory response to steatotic liver disease stimuli.

We are seeking a PhD-level scientist to support experimental research within the Hepatology team, with a primary focus on macrophage biology and co-culture model development. The successful candidate will design and execute laboratory experiments to progress a macrophage-fibroblast co-culture system, contributing to ongoing liver fibrosis modeling initiatives.

This role involves hands-on laboratory work, experimental design, data analysis, and close collaboration with internal scientific stakeholders.

-Design, develop, and execute macrophage-based co-culture assays to support liver fibrosis modeling

-Perform in-vitro experiments involving macrophages and fibroblasts, including co-culture system optimization

-Generate proof-of-concept data demonstrating fibrotic macrophage activation of liver fibroblasts

-Utilize flow cytometry and imaging techniques to characterize immune cell populations and cellular responses

-Analyze, interpret, and document experimental data to inform model development and decision-making

-Collaborate with hepatology and disease area scientists to align experimental outcomes with project objectives

-Contribute to experimental planning, troubleshooting, and continuous improvement of assay workflows

We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment regardless of their race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or recruiting process, please send a request to [email protected] learn more about how we collect, keep, and process your private information, please review Insight Global's Workforce Privacy Policy:

Skills and Requirements

PhD in Immunology, Cell Biology, Biology, Biomedical Sciences, or a related discipline

Strong hands-on experience in immunological cell-based assays

Proven expertise in flow cytometry, microscopy & RNA analysis

Background in liver biology, fibrosis, or inflammatory disease models Clinical Trial Design

Posted 2026-04-09

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