CQV Engineers

cGxPServe
Spring House, PA
Job Description:
The scope includes thermal mapping and qualification of various GMP equipment, with a strong focus on controlled temperature units and laboratory devices.

Responsibilities:
  • Preparation and execution of Qualification Protocols and Reports.
  • Design Qualification (DQ.).
  • Installation Qualification (IQ).
  • Operational Qualification (OQ.).
  • Performance Qualification (PQ.).
  • Review and/or authoring of supporting validation documentation.
  • User Requirements Specifications (URS.).
  • Risk Assessments (e.g., SIA.).
  • Commissioning Test Report.
  • Thermal mapping strategy definition and execution.
  • Execution of FAT/SAT, where applicable.
  • PCOM/CTP support and walkdown activities.
  • Support during regulatory inspections and internal audits.
Requirements:
  • Equipment qualification in GMP-regulated environments.
  • Temperature mapping and calibration.
  • Understanding of GAMP5 principles.
  • Good documentation practices (GDP.).
  • Capability to handle multiple systems in parallel, following a risk-based approach to prioritize tasks.
  • Experience in authoring and reviewing validation protocols and reports, including deviation management.
Equipment in Scope:
  • Controlled Temperature Units & Storage:
  • Cryogenic Freezers.
  • Ultra-low Freezers (-80 C.)
  • Standard Freezers (-20 C.)
  • Refrigerators.
  • CO2 Incubators.
  • General Incubators.
  • Ovens.
  • Stability Chambers.
Safety & Laboratory Equipment:
  • Biosafety Cabinets.
  • Fume Hoods.
  • Flammable Cabinets.
  • Lyophilises
  • Cryostats.
HVAC and Air Handling:
  • AHUs (Air Handling Units.)
  • Room HVAC systems (supply/exhaust units.)
  • HVAC Controls and Sensors.
  • Client-connected ventilation devices.
Clean Utilities:
  • Purified Water (PW) Distribution System.
  • Clean Steam Supply.
  • Clean Compressed Air.
  • Nitrogen Lines for Clean Applications.
  • WFI (if confirmed in detailed docs.)
Black Utilities:
  • Electrical Panels and Subpanels.
  • General Lighting and Emergency Power.
  • Power Supply to Equipment.
  • Grounding Systems.
  • Compressed Air for Technical Use.
  • Cooling/Heating loops (non-GMP.)
Monitoring and Control Systems:
  • Environmental Monitoring System (EMS.).
  • Building Management System (Client.).
  • Temperature and Humidity Sensors.
  • Alarming and Notification Panels.
Posted 2025-08-07

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