Innovative Therapies Project Manager (Hiring Immediately)

Jazz Pharmaceuticals
Philadelphia, PA

If you are a current Jazz employee please apply via the Internal Career site.

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information.

Essential Functions:

  • Serve as the leader of one (or more) cross functional EDT(s) with accountability for product strategy and operational execution from IND to POC .

  • Establish a vision and strategy for the product with the EDT, and relevant functional matrix teams.

  • Leverage input from all critical functions to identify and evaluate strategic global product development opportunities that optimize the value for our patients through optimal balance of risk, timelines, cost and revenue.

  • Participate in the Long Range Plan (LRP) process and approve underlying assumptions resulting in articulate strategies and plans that align with Jazz’s mission and approach.

  • Develop global Integrated Product Development Plans (iPDPs) for governance approval and provide oversight for EDT contributions for regulatory filings (IND, CTA).

  • Lead and drive team accountability and effectiveness by setting clear expectations for the EDT and team members’ roles and responsibilities. Promote team cohesiveness to optimize performance, mediating conflict resolution and embedding Diversity, Equity, Inclusion, and Belonging.

  • Provide strategic guidance and support to EDT functional matrix teams and activities that are executed in matrix and functional channels (e.g. clinical development, technical operations, commercial, regulatory).

  • Mentor team members, constructively challenge strategies, set expectation for decision quality and provide performance review input for key positions on the LDT.

  • Mobilize and align the organization to execute on the approved product strategy, including coordination and synchronizing activities with other EDTs and/or functional matrix teams.

  • Accountable for project budget, timelines and resource requirements in collaboration with the team members, Project Management and finance.

  • Collaborate with functional heads to confirm required roles and nomination of key EDT members.

  • Proactively engage with leaders in the organization to establish and align on development strategy, through identification of alternatives, tradeoffs, and interdependencies to optimize the value of the product, and prepare for stage gate presentations to the Early Development Project Review Committee (EDPRC) or Development Project Review Committee (DPRC) and Portfolio Governance Committee (PGC).

  • Ensure the timely escalation of realized risks and issues to senior leaders, DPRC and other review/decision-making/governance committees.

  • May be required to take on additional responsibility for external collaborations and/or corporate strategic projects with high visibility and expanded team leadership responsibilities including participation in external due diligence for in-licensing opportunities. This may include participation or leadership on Strategic Partnership Joint Governance Committee and/or Working Teams.

  • Contribute to disease area assessments and other portfolio level cross-molecule initiatives.

  • Partner with relevant functions to develop effective working relationships both internally and with external key stakeholders (development partners, key opinion leaders, advocacy groups, etc.).

  • As appropriate, participate in ongoing development and enhancement of cross-functional team structures, processes, systems, and other tools and resources.

Required Knowledge, Skills, and Abilities:

  • +15 years global multi-disciplinary drug development experience in the pharma/biotech industry with key roles or leadership in development programs and a proven track record of innovation and balancing program risks with speed.

  • Proven experience as a successful, decisive leader in a strategic multi-functional environment with a track record of delivering results through effective matrix teams and peer leadership.

  • Proven ability to define and communicate a compelling long-term vision and engage and lead global cross-functional teams to develop an aligned strategy

  • Prior experience in large scale early phase Solid Tumor Oncology drug development and regulatory submissions (IND, CTA) with proven ability to lead multiple highly complex and/or high priority projects.

  • Experience managing and/or leading collaborations, alliances, or other relationships through influencing without direct authority, creating effective relationships with peer counterparts in an alliance.

  • An effective problem solver with an entrepreneurial mindset who can find creative solutions to drug development challenges.

  • Ability to synthesize different points of view to make sound, timely and objective decisions. Cross-cultural and cross-organizational management and collaboration skills.

  • Proven capability to lead, motivate, inspire without authority in a diverse, global, cross-functional matrix structure

  • Demonstrated leadership and action in diversity and inclusion

  • Independent, self-motivated individual with a highly entrepreneurial style coupled with collaborative and positive leadership

  • Strong and influential communicator: exceptional influencing skills that demonstrate strong thought partnership and create effective relationships with internal and external stakeholders

Required/Preferred Education and Licenses:

  • Advanced degree (MD, PhD, PharmD) required

Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.

FOR US BASED CANDIDATES ONLY

Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $270,400.00 - $405,600.00

Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.

At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .

Posted 2026-04-30

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