Spring TDS Proteins API CEAS Analytical Co-Op

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Job Function:

Career Programs

Job Sub Function:

Non-LDP Intern/Co-Op

Job Category:

Career Program

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

Johnson & Johnson Innovative Medicine is recruiting for a Spring TDS Proteins API CEAS Analytical Co-Op, located in Spring house, PA.

Research & Development Co-op Overview:

J&J R&D encompasses the development of sophisticated materials, process improvements, risk management and mechanical testing through the development process across all sectors including Pharmaceutical, Medical Device, Consumer and Corporate/Enterprise.

We offer a fast-paced cross-functional, technologically advanced, corporate environment, passionate about developing individual engineering and scientific skills. You will have the opportunity to learn about anatomy, disease states, deformities and the surgical procedure/products used to address these conditions.

Life as an R&D Co-op:

The R&D Co-op program provides each student with real-life hands-on experience, coaching and mentoring, networking opportunities, as well as the opportunity to meet people from various schools throughout the country. Each Co-op will be assigned to a single function with a specific project for the 6-month term.

The typical Co-op term is from Jan 2026– Jun 2026.

Key Responsibilities:

The TDS Proteins Development API organization is seeking a candidate interested in protein process development. Release glycan analysis is a critical quality attribute for therapeutic antibodies to determine the glycosylation profile which can impact efficacy, safety and stability of the molecule. There are multiple techniques available to analyze glycans from sample preparation to detection. Glycans can be released enzymatically and analyzed via mass spectrometry for more detailed structural information using minimal sample amount. Alternatively, the released glycans can be fluorescently labeled and run using either hydrophilic interaction liquid chromatography (HILIC) releasing glycans based on polarity or by capillary electrophoresis; these techniques offer high-resolution separation and quantification. The current method in CEAS-Analytical is via reduced mass spectrometry while analytical development typically runs a HILIC method to quantify glycans. Sciex has introduced a release glycan kit for use on the Biophase which could prove useful for quantification of glycans. In this role, the Co-Op will...

• C ompare these techniques to examine the feasibility and benefit of adding a labeled release glycan analysis to the CEAS-Analytical workflow. This will impact the business by bridging the gap between CEAS and downstream process development for oligosaccharide quantification.

• Analyze and interpret experimental results using analytical and statistical techniques. Actively participate in weekly meetings with internal and external collaborators.

• Participate in technical discussions on design of experiments to fill gaps in knowledge.

• Maintain a laboratory notebook and other technical documents according to required guidelines.

• Provide other project support as needed.

Qualifications

Education:

• Analytical Chemistry, Biochemistry, Molecular Biology, Chemical Engineering, Biological Engineering, and related majors are preferred.

• Candidates must be actively enrolled in an accredited University for the duration of a co-op assignment pursuing a Bachelor’s or equivalent experience, Master’s, or PhD degree or equivalent experience. For students pursuing their Bachelor's degree or equivalent experience, Juniors or Seniors are preferred.

• Minimum GPA of 2.8 is required.

• Completion of Undergraduate Freshmen year at an accredited University is required.

Experience and Skills:

Required:

• Candidate must be legally authorized to work in the U.S. and must not require sponsorship for employment visa status now or in the future (e.g., FI, H1-B status)

• Ability to demonstrate strong analytical and quantitative skills is required

• Excellent communication, presentation, and leadership skills are preferred

• Ability to balance multiple projects and initiatives while performing results

• Must be a self-starter works independently while supplying to the team goals

• Proven leadership/participation with campus programs and/or community service activities is desired

Preferred:

• Students with basic laboratory skills and experience in research, experimental design & execution, and data analysis preferred.

• Students with prior experience with liquid chromatography and capillary electrophoresis separation techniques, as well as knowledge of glycosylation and protein structure.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via . internal employees contact AskGS to be directed to your accommodation resource.